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If you want to get back your youthful appearance and erase facial wrinkles, you will love what Daxxify has to offer.

Daxxify is the trade name of DaxibotulinumtoxinA. 

This FDA-approved injectable treatment uses a powerful peptide ingredient that works to smooth your facial skin and provides long-lasting results you won’t find with other anti-wrinkle injections. Want to know more? Keep reading to find out why Daxxify is your best choice when it comes to cosmetic treatment options for wrinkles and frown lines. 

What is Daxxify? 

Free Crop unemotional mature female applying anti aging moisturizing eye patches and looking away in light room Stock Photo

Daxxify is an FDA-approved anti-wrinkle treatment and injectable treatment that promises smoother, more youthful-looking skin and is one of the top frown line treatments available on the market today. It’s ideal for treating glabellar lines (the area between the eyebrows), forehead lines and wrinkles around the eyes. 

Classified as a neuromodulator, Daxxify is in the same class as Botox, Jeaveau, Xeomin and Dysport. All of these work by the release of neurotransmitters to block nerve signals that reduce muscle contraction helping to reduce the appearance of wrinkles. One of the biggest complaints that clients have with these older versions of neurotoxins is that they don’t last long enough.

Daxxify does not contain any human or animal byproducts or blood products as a stabilizer, though it does still have a neurotoxin content. Older methods use human serum albumin or cow’s milk protein to stabilize the botulinum toxin type A. One of the active ingredients in Daxxify is a peptide, which is a natural ingredient that promises longer-lasting results. The treatment can last for up to 6 full months, or an entire year with two treatments. Some patients even see results for 9 months after treatment.

How Does Daxxify Work?

As mentioned above, Daxxify utilizes a novel peptide in its formulation, which, when injected into the skin, alters the function of your facial muscles, blocking the associated chemical signals (it actually inhibits the release of acetylcholine), which in turn smooths out wrinkles and lines.

Specifically, when the muscles responsible for frowning are “frozen,” it means that your wrinkles are less noticeable. The effect is similar for the muscles involved with smiling and can create a smoother appearance on the forehead and around the eyes as well. It works equally well on horizontal lines and vertical lines. 

Daxxify injection treatment won’t interfere with your facial expressions and may even help prevent the future formation of wrinkles in the treated areas. Done correctly, the only noticeable difference in your facial features is smoother skin and a more youthful look. 

With a single procedure of the active core neurotoxin, you may notice that the results last 6 to 9 months after treatment. This was demonstrated in the clinical trial of the product which showed a duration of up to 6-9 months in 50% of the participants. 

Treatment Process 

Free Woman Getting a Facial Treatment Stock Photo daxxify

Before Daxxify

Before undergoing a Daxxify injection treatment, it’s a good idea to know what to expect, other than younger-looking skin.

The treatment process begins before the first cycles of treatment, as there are some steps you will need to take to be prepared for your appointment. Even if you are only planning to undergo a single treatment, it’s important to be ready. It’s also vital that you choose a qualified injector or other qualified healthcare professional to carry out the procedure.

The most important way to be prepared is to avoid certain medications and supplements, including several over-the-counter medicines and many prescription medicine products for two weeks prior to your procedure, such as

  • Blood thinners
  • Topical steroids
  • Allergy medications
  • Aspirin
  • St. John’s Wort
  • Ibuprofen
  • Retin-A
  • Fish oil and omega 3s
  • Muscle relaxants
  • Sleep medications
  • Sleep supplements
  • Vitamin E and supplements containing vitamin E

This is not an exhaustive list and it’s very important to let your injector know any and all medications, supplements and herbal remedies that you take during your personal consultation. Other pre-treatment instructions may include the following:

  • Avoid alcohol for 2 to 3 days before treatment
  • Apply any topical creams (if prescribed) according to directions

Additionally, during your initial consultation, you will discuss your treatment goals. This allows your aesthetic provider to create a personalized treatment plan that meets your needs. This includes the frequency of regular treatments at a consistent duration for the best results, as well as any concerns and questions you have about Daxxify. 

During Daxxify

There are also a wide variety of things to expect during this cosmetic procedure. The first step is to cleanse your skin. Some providers also offer the option to numb the area being treated to control the mild pain you might experience during the injections.

Next, you will be asked to make specific facial expressions, which enable your dermatologist to determine the best treatment sites on your face to produce natural-looking results. This will differ for each individual patient, based on how and where your wrinkles have appeared. 

Finally, Daxxify is injected into the chosen places. You may experience minor pain and/or stinging with each injection, which is done with a very fine needle. The procedure typically lasts 10 to 15 minutes and thanks to minimal downtime, you can return to your normal activities right away. Most patients report a noticeable improvement in the appearance of frown lines in the first two days after treatment. Full results should be noticeable about two weeks after injection.

After Daxxify

It’s important to follow aftercare instructions very carefully after the procedure is complete. This ensures the most optimal results and cuts down on the risk of side effects (though it won’t prevent them altogether). You may be asked to do the following after your injections:

  • Avoid any strenuous activity after treatment (the timing depends on each individual patient)
  • Don’t touch the injection sites
  • Use ice packs (as recommended by your dermatologist) to control pain and swelling
  • Apply any prescribed topical treatments according to the directions.

One of the reasons why patients choose Daxxify injectable treatment is because it tends to work faster and last longer than other anti-wrinkle injectables. You may notice that your muscle function begins slowly returning to normal about 4-6 months after treatment, which lets you know that it’s time to schedule one of your next cycles of treatment. 

Benefits of Daxxify 


As you’ve probably already gathered from reading above, there are several benefits to choosing Daxxify to smooth your facial lines and dynamic wrinkles. It’s a top choice among aesthetic treatments for frown lines, as well as other wrinkles on the face and leaves you with smoother skin and the youthful-looking appearance you desire.

Here are the top five benefits you can expect:

Long lasting results: The most impressive benefit is that it has greater longevity than other neuromodulator products.  Clinical studies show that you can expect results for 6 to 9 months after initial treatment in up to 50% of participants. This longevity means you may only need two treatments a year for continued results. 

Efficacy: Daxxify is an effective treatment for all areas of the face including the forehead and the jawline. It works well on severe lines, including frown lines, forehead wrinkles and crow’s feet. Fine lines, shallow wrinkles and other signs of aging simply fade away.

Early Onset of effects: The results of Daxxify can be seen as early as 24-72 hours after treatment, much faster than Botox and other similar products. Full effects can be seen after 2 weeks. 

Cost Efficiency: Because the results enjoy a prolonged duration compared to other cosmetic injectables, you need fewer treatments for maintenance – two per year compared to three or four. This is a definite cost saving. 

Medical Safety: Of course, there are risks with any injection procedure, even FDA-approved treatments, but Daxxify is a non-surgical and non-invasive procedure with minimal risks when performed by a board-certified plastic surgeon or other qualified healthcare professional. There is little preparation, a short procedure time and minimal downtime for recovery. There are also minimal side effects.

Vegan-friendly: Because it does not contain any human or animal products in its formula, Daxxify is a neurotoxin treatment suitable for vegetarians and vegans. 

On top of this are the emotional benefits. Daxxify satisfies the reasons why people choose these cosmetic procedures. Looking better gives a boost to self-esteem and self-confidence, both positive factors in mental health. 

Benefits are maximized when you follow instructions carefully, both before and after your treatment. Your benefit profile may differ from another patient’s based on your goals and skin type. The treatment response in patients may also differ from patient to patient so be sure you understand what you can expect before getting started. 


While qualified patients aren’t likely to experience any severe risks from Daxxify, there are some common side effects that you might have to deal with, as well as some potential risks that you should be on the lookout for.

Many safety studies have been conducted so that you can understand the risks and weigh them with the benefits before you use Daxxify, or any other cosmetic treatment using botulinum toxin. Most patients are able to get back to their daily routine immediately following the treatment. Here are some of the side effects that are common after Daxxify injectable treatment:

  • Redness
  • Bruising 
  • Swelling
  • Itching
  • Pain
  • Drooping eyelid
  • Frozen facial features
  • Headache
  • Dry eye/reduced blinking

While these side effects are common, if any of them cause you alarm or concern, let your cosmetic doctor know. There are also some symptoms that warrant an immediate call to your physician. They include the following:

  • Trouble breathing
  • Irregular heartbeat
  • Difficulty swallowing
  • Hives on the face, lips or tongue
  • Allergic reaction
  • Fever
  • Rashes
  • Muscle spasms
  • Excessive muscle weakness
  • Skin infection
  • Worsening of any pre-existing medical conditions, including skin conditions

There are some individuals who should avoid Daxxify:

  • Patients with an allergy or adverse event after a previous treatment using botulinum toxin
  • Patients with acute skin conditions in the treatment area, especially during a flare-up
  • Those with a diagnosed bleeding disorder should use caution
  • Women who are pregnant or nursing

Remember that the best way to have Daxxify is with a personalized treatment plan devised by a fully qualified healthcare provider. Daxxify is backed by clinical studies that emphasize its safety and effectiveness for most qualified patients. 


The important thing to remember when considering Daxxify is that it’s a good choice for dynamic frown lines and more severe wrinkles and lines on the face which result from years of muscle movement. Backed by extensive research and clinical trials, and with an impressive safety profile, this botulinum toxin product offers impressive results with very little downtime. It’s great for many individual patients with a proven duration of efficacy that surpasses all other neuromodulators on the market.

If you’re ready to give it a try, set up a personal consultation with the Z Center for Cosmetic Health today and we can help you get started.